Overview

Providing an Agile Approach to Diagnostic Platform and Method Selection

MolecularMD collaborates with the most prominent platform manufacturers, and has development agreements in place that enable a path to an in-vitro diagnostic designation for codeveloped diagnostic assays. MMD pursues Certified Service Provider designations from best in class platform companies which ensures laboratory proficiency and provides a higher level of technical support. It is MMD’s philosophy to collaborate and partner with a diverse range of diagnostic platform manufacturers in order to have access to the technologies that best fits its clients’ needs for clinical trial assays and in-vitro diagnostics. Limiting a drug program to a single diagnostic platform early in the development of a diagnostic assay can lead to higher costs and can introduce unnecessary risks. MMD’s solutions are designed to manage the risk and uncertainty associated with the oncology codevelopment process and are agile, capable of adapting to changes in strategy. Platform diversity combined with broad development and deployment capabilities are attributes that our clients value. MMD leverages technologies that address all major types of biomarkers and pair them with the most ideal diagnostic platforms and validated methods available.

Technologies and Platforms

Application Methods Platforms /Technologies
DNA Mutation Detection & Analysis Next Generation Sequencing
Sanger Sequencing
Allele-Specific PCR
Digital PCR
ABI 3730xl
ABI 7500 Fast Dx*
BioRad QX200
Illumina MiSeq
Ion Torrent PGM
Ion Torrent S5
Qiagen Rotor Gene Q MDx*
QuantStudio Dx*
Gene Expression Analysis RT-qPCR
Digital Color Barcodes (multiplex)
ABI 7500 Fast Dx*
Nanostring nCounter
Qiagen Rotor Gene Q MDx*
QuantStudio Dx*
Protein Expression Analysis Immunohistochemistry (IHC)
Digital Pathology Imaging & Quantitative Analysis
Indica Labs HALO®
Leica Aperio*
Leica Bond III*
Tissue Phenomics
Ventana Benchmark
Ventana iScan Coreo
Structural Variation
Detection & Analysis
(CNV, Fusions & Translocations)
Next Generation Sequencing
CISH/SISH
Abbott Vysis
ABI 3500xL Dx*
Archer AMP Chemistry
Illumina MiSeq
Ion Torrent PGM
Ion Torrent S5
Leica Bond III*
Ventana Benchmark
Liquid Biopsy/ctDNA Next Generation Sequencing
Digital PCR
Bio-Rad QX200
Illumina MiSeq
Ion Torrent PGM
DNA/RNA Extraction Manual & Automated PAXgene® Blood RNA System*
Promega Maxwell CSC*
Qiagen QIAcube

*FDA Cleared