Clinical Development

Laboratory Scientist, Immunohistochemistry and Histopathology Tissue Diagnostics

Location: Portland, Oregon
Type: Full-Time

MolecularMD is expanding its Tissue Diagnostics group and seeks to hire a highly motivated, experienced Scientist to develop and validate tissue-based immunohistochemical biomarker assays that will support multiple oncology therapeutic drug development programs for biopharma sponsors. This position will have responsibility for assisting in generation of project proposals and budgets, design and execution of experiments, as well as data analysis and reporting for both development and clinical trial programs.

Education and Work Experience:

  • A Ph.D. or similar advanced degree in Biological Sciences, with 1-3 years of professional experience in oncology biomarker research or clinical development, or
  • An M.S or similar degree in Biological Sciences, with 3-5 years of professional experience in oncology biomarker research or clinical development, or
  • A B.S. or similar degree in Biological Sciences, with 5-10 years of professional experience in oncology biomarker research or clinical development

Previous work experience in the biopharmaceutical industry, including Contract Research Organizations (CROs), is strongly preferred. Prior experience in a CLIA/CAP (Clinical Laboratory) environment is strongly preferred.

Essential Duties and Responsibilities (and other duties, as assigned):

  • A solid working knowledge of histopathology lab workflow, including, but not limited to:
  • Acquisition, management and banking of FFPE tissue specimens
  • Routine FFPE tissue sectioning and staining (H&E)
  • Whole-slide scanning of stained microscope slides and annotation of digital slide images
  • Timely and accurate reporting of results in LIS/LIMS databases
  • Demonstrated expertise in the development of novel immunohistochemistry (IHC) and in situhybridization (ISH) slide-based assays on automated IHC/ISH platforms (Leica, Ventana)
  • Perform clinical sample testing according to laboratory SOPs
  • Plan and execute assay development and validation projects
  • Draft SOPs, validation plans and validation reports
  • Write and/or maintain documentation, such as SOPs and work instructions, for equipment, processes and protocols as needed

Qualifications

  • Strong knowledge of cancer biology and a record of successful contribution to oncology therapeutic and/or diagnostic development projects/programs
  • Strong motivation and demonstrated excellent technical skills suited for work in a regulated, clinical diagnostic laboratory environment
  • Demonstrated innovative thinking and analytical problem solving skills
  • Excellent technical writing, communication and computer skills
  • Ability to multi-task and align priorities according to changing project needs
  • Maintain excellent laboratory records as required by Good Documentation Practices (GDP) and company policies
  • Experience with multiplex IHC/ISH technologies and/or automated image analysis is a plus

If you are interested in joining our team and would like to be considered for a future job opening, please email your resume to: human_resources@molecularmd.com

MolecularMD is an equal opportunity employer. It is the policy of MolecularMD to prohibit discrimination of any type and to afford equal employment opportunities to employees and applicants, without regard to race, color, religion, gender (sex), age, national origin, sexual orientation, gender identity, disability, genetic information, veteran status or any other characteristic protected by law.